Selected publications are shown below. Please visit Ben’s Google Scholar for a full list of publications.

2026

Stefano J*, Elcavage LE*, Hong S-J, Bartel DP, Kleaveland B. Derepression of a single microRNA target causes female infertility in mice. Nucleic Acids Research. 2026 Jan; gkaf1357. DOI: 10.1093/nar/gkaf1357 *co-first authors

2025

Stefano J*, Elcavage LE*, Hong S-J, Bartel DP, Kleaveland B. Derepression of a single miRNA target causes female infertility in mice. https://www.biorxiv.org/content/10.1101/2025.04.29.651088v1 *co-first authors

2024

Buhagiar AF and Kleaveland B. To kill a microRNA: emerging concepts in target-directed microRNA degradation. Nucleic Acids Research. 2024 Feb. PMID: 38224449. DOI: 10.1093/nar/gkae003

2023

Kleaveland B. Target-directed microRNA degradation. Cell. 2023 Dec; 186(25): 5674. PMID: 38065084. DOI: 10.1016/j.cell.2023.11.020

Shi CY, Elcavage LE, Chivukula RR, Stefano J, Kleaveland B, Bartel DP. ZSWIM8 destabilizes many murine miRNAs and is required for proper embryonic growth and development. Genome Research. 2023. PMID: 37532519, PMCID: PMC10620050. DOI: 10.1101/gr.278073.123

2020

Shi CY, Kingston ER, Kleaveland B, Lin DH, Stubna MW, Bartel DP. The ZSWIM8 ubiquitin ligase mediates target-directed microRNA degradation. Science. 2020 Dec 18; 370(6523). PMID: 33184237, PMCID: PMC8356967. DOI: 10.1126/science.abc93

2018

Kleaveland B, Shi CY, Stefano J, Bartel DP. A network of noncoding regulatory RNAs acts in the mammalian brain. Cell. 2018 July; 174(2) 350-362. PMID: 29887379, PMCID: PMC6559361. DOI: 10.1016/j.cell.2018.05.022

pre-2018

Kleaveland B, Zheng X, Liu JJ, Blum Y, Tung JJ, Zou Z, Sweeney SM, Chen M, Guo L, Lu M, Zhou D, Kitajewski J, Affolter M, Ginsberg MH, Kahn ML.  Regulation of cardiovascular development and integrity by the heart of glass-cerebral cavernous malformation protein pathway.  Nature Medicine.  2009 February; 15(2): 169-176. PMID: 19151727, PMCID: PMC2665266. DOI: 10.1038/nm.1918